^ Jump up to: a b c "FDA warns company marketing unapproved cannabidiol products with unsubstantiated claims to treat cancer, Alzheimer's disease, opioid withdrawal, pain and pet anxiety". US Food and Drug Administration. July 23, 2019. Retrieved July 24, 2019. Unlike drugs approved by the FDA, the manufacturing process of these products has not been subject to FDA review as part of the drug approval process, and there has been no FDA evaluation of whether these products are effective for their intended use, what the proper dosage is, how they could interact with FDA-approved drugs, or whether they have dangerous side effects or other safety concerns.
Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner. In vitro, cannabidiol inhibited receptors affecting the activity of voltage-dependent sodium and potassium channels, which may affect neural activity. A small clinical trial reported that CBD partially inhibited the CYP2C-catalyzed hydroxylation of THC to 11-OH-THC. Little is known about potential drug interactions, but CBD-mediates a decrease in clobazam metabolism.
Psychoactive – Any chemical substance that can enter the brain from the bloodstream and directly affect the central nervous system is considered psychoactive. Many psychoactive substances have medical applications (such as anesthetics, psychiatric drugs, etc.), but some of these substances are used solely for recreation, causing dangerous side effects and addiction.
Cannabidiol can be taken into the body in multiple ways, including by inhalation of cannabis smoke or vapor, as an aerosol spray into the cheek, and by mouth. It may be supplied as CBD oil containing only CBD as the active ingredient (no included tetrahydrocannabinol [THC] or terpenes), a full-plant CBD-dominant hemp extract oil, capsules, dried cannabis, or as a prescription liquid solution. CBD does not have the same psychoactivity as THC, and may change the effects of THC on the body if both are present. As of 2018, the mechanism of action for its biological effects has not been determined.
I was introduced to vaping from a friend who smoked 2-3 packages of cigarettes a day. I smoked only about a half package per day, but decided to try it. I always hated the way cigarettes made my lungs feel so heavy and my throat feel soar. As most people ,I was addicted to smoking from an early age in my life. I decided to try vaping, but still had a few cigarettes per day. As time went on I enjoyed the taste of the flavor and that it didn’t make your house smell. I now have several vape pens and enjoy many different flavors, and now free from regular cigarettes. I have heard of a disease that you can get from vaping called popcorn lung, I have yet to research this but that will be my next project.
They’re just saying if you haven’t already been introduced to nicotine, why start? Nicotine is a habit forming drug and vaping has Nicotine in it’s Vape juices… but if you intend on Vaping @ 0% Nicotine, then you are Right, it wouldn’t be a problem… but sometimes temptation for kids in school for instance, Vaping for leads to adding that nicotine to the equation… cannabidiol